Unveiling Early Breast Cancer: A Research Exploration of Nanoparticle Sensors for Urine-Based Detection

Abstract

Nanoparticle sensor technology presents a promising avenue for the early detection of cancer, notably in breast cancer screening. This study delves into the creation of a nanoparticle-driven sensor platform tailored for the detection of breast cancer biomarkers in urine samples. Gold nanoparticles (AuNPs) underwent synthesis and subsequent functionalization to selectively capture specific biomarkers associated with breast cancer. The sensor's validity was established through diverse assays, including surface-enhanced Raman spectroscopy (SERS) and colorimetric assays. The findings affirm the platform's viability and effectiveness in identifying breast cancer biomarkers in urine samples, offering a non-invasive modality with prospective clinical applications.